Characteristics and Outcomes of Pediatric Patients With Ebola Virus Disease Admitted to Treatment Units in Liberia and Sierra Leone: A Retrospective Cohort Study.

ABSTRACT:

Background

The clinical and virologic characteristics of Ebola virus disease (EVD) in children have not been thoroughly documented.

Methods

Consecutive children aged <18 years with real-time polymerase chain reaction (RT-PCR)-confirmed EVD were enrolled retrospectively in 5 Ebola treatment units in Liberia and Sierra Leone in 2014/2015. Data collection and medical management were based on standardized International Medical Corps protocols. We performed descriptive statistics, multivariate logistic regression, and Kaplan-Meier survival analyses.

Results

Of 122 children enrolled, the median age was 7 years and one-third were aged <5 years. The female-to-male ratio was 1.3. The most common clinical features at triage and during hospitalization were fever, weakness, anore

SUBMITTER: Smit MA 

PROVIDER: S-EPMC5241778 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature