Temporal behavior of seizures and interictal bursts in prolonged intracranial recordings from epileptic canines.

ABSTRACT:

Objective

Epilepsy is a chronic disorder, but seizure recordings are usually obtained in the acute setting. The chronic behavior of seizures and the interictal bursts that sometimes initiate them is unknown. We investigate the variability of these electrographic patterns over an extended period of time using chronic intracranial recordings in canine epilepsy.

Methods

Continuous, yearlong intracranial electroencephalography (iEEG) recordings from four dogs with naturally occurring epilepsy were analyzed for seizures and interictal bursts. Following automated detection and clinician verification of interictal bursts and seizures, temporal trends of seizures, burst count, and burst-burst similarities were determined. One dog developed status epilepticus, the recordings of which

SUBMITTER: Ung H 

PROVIDER: S-EPMC5241889 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature