An improved genome assembly uncovers prolific tandem repeats in Atlantic cod.

ABSTRACT:

Background

The first Atlantic cod (Gadus morhua) genome assembly published in 2011 was one of the early genome assemblies exclusively based on high-throughput 454 pyrosequencing. Since then, rapid advances in sequencing technologies have led to a multitude of assemblies generated for complex genomes, although many of these are of a fragmented nature with a significant fraction of bases in gaps. The development of long-read sequencing and improved software now enable the generation of more contiguous genome assemblies.

Results

By combining data from Illumina, 454 and the longer PacBio sequencing technologies, as well as integrating the results of multiple assembly programs, we have created a substantially improved version of the Atlantic cod genome assembly. The sequence cont

SUBMITTER: Torresen OK 

PROVIDER: S-EPMC5241972 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature