Preventing Depression in Adults With Subthreshold Depression: Health-Economic Evaluation Alongside a Pragmatic Randomized Controlled Trial of a Web-Based Intervention.

ABSTRACT:

Background

Psychological interventions for the prevention of depression might be a cost-effective way to reduce the burden associated with depressive disorders.

Objective

To evaluate the cost-effectiveness of a Web-based guided self-help intervention to prevent major depressive disorder (MDD) in people with subthreshold depression (sD).

Methods

A pragmatic randomized controlled trial was conducted with follow-up at 12 months. Participants were recruited from the general population via a large statutory health insurance company and an open access website. Participants were randomized to a Web-based guided self-help intervention (ie, cognitive-behavioral therapy and problem-solving therapy assisted by supervised graduate students or health care professionals) in additio

SUBMITTER: Buntrock C 

PROVIDER: S-EPMC5244034 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature