The efficacy of psychotherapy, pharmacotherapy and their combination on functioning and quality of life in depression: a meta-analysis.

ABSTRACT:

Background

There is growing recognition of the importance of both functioning and quality of life (QoL) outcomes in the treatment of depressive disorders, but the meta-analytic evidence is scarce. The objective of this meta-analysis of randomized controlled trials (RCTs) was to determine the absolute and relative effects of psychotherapy, pharmacotherapy and their combination on functioning and QoL in patients with depression.

Method

One hundred and fifty-three outcome trials involving 29 879 participants with depressive disorders were identified through database searches in Pubmed, PsycINFO and the Cochrane Central Register of Controlled Trials.

Results

Compared to control conditions, psychotherapy and pharmacotherapy yielded small to moderate effect sizes for functi

SUBMITTER: Kamenov K 

PROVIDER: S-EPMC5244449 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature