Inactivity periods and postural change speed can explain atypical postural change patterns of Caenorhabditis elegans mutants.

ABSTRACT:

Background

With rapid advances in genome sequencing and editing technologies, systematic and quantitative analysis of animal behavior is expected to be another key to facilitating data-driven behavioral genetics. The nematode Caenorhabditis elegans is a model organism in this field. Several video-tracking systems are available for automatically recording behavioral data for the nematode, but computational methods for analyzing these data are still under development.

Results

In this study, we applied the Gaussian mixture model-based binning method to time-series postural data for 322 C. elegans strains. We revealed that the occurrence patterns of the postural states and the transition patterns among these states have a relationship as expected, and such a relationship must be

SUBMITTER: Fukunaga T 

PROVIDER: S-EPMC5244558 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature