Prostate cancer bone metastases on staging prostate MRI: prevalence and clinical features associated with their diagnosis.

ABSTRACT:

Purpose

Bone lesions on prostate MRI often raise concern about metastases. This study aimed to evaluate the prevalence of bone metastases on staging prostate MRI and evaluate associations between their MRI features and clinical/pathologic characteristics.

Methods

Retrospective, IRB-approved study of 3765 patients undergoing prostate MRI for newly diagnosed PCa between 2000 and 2014. The reference standard to calculate the prevalence of bone metastases was bone biopsy and/or ≥1-year follow-up after MRI. In a subsample of 228 patients, the MRI characteristics of bone lesions were recorded by two radiologists independently. Associations between MRI and clinical/pathologic findings, including National Comprehensive Cancer Network (NCCN) risk categories, were calculated.

Resul

SUBMITTER: Vargas HA 

PROVIDER: S-EPMC5247358 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature