Candida antifungal drug resistance in sub-Saharan African populations: A systematic review.

ABSTRACT: Background: Candida infections are responsible for increased morbidity and mortality rates in at-risk patients, especially in developing countries where there is limited access to antifungal drugs and a high burden of HIV co-infection.  Objectives: This study aimed to identify antifungal drug resistance patterns within the subcontinent of Africa.  Methods: A literature search was conducted on published studies that employed antifungal susceptibility testing on clinical Candida isolates from sub-Saharan African countries using Pubmed and Google Scholar.  Results: A total of 21 studies from 8 countries constituted this review. Only studies conducted in sub-Saharan Africa and employing antifungal drug susceptibility testing were included. Regional dif

SUBMITTER: Africa CW 

PROVIDER: S-EPMC5247777 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature