Association between Increased Gastric Juice Acidity and Sliding Hiatal Hernia Development in Humans.

ABSTRACT:

Objectives

Several clinical factors; overweight, male gender and increasing age, have been implicated as the etiology of hiatal hernia. Esophageal shortening due to acid perfusion in the lower esophagus has been suggested as the etiological mechanism. However, little is known about the correlation between gastric acidity and sliding hiatus hernia formation. This study examined whether increased gastric acid secretion is associated with an endoscopic diagnosis of hiatal hernia.

Methods

A total of 286 consecutive asymptomatic patients (64 were diagnosed as having a hiatal hernia) who underwent upper gastrointestinal endoscopy were studied. Clinical findings including fasting gastric juice pH as an indicator of acid secretion, age, sex, body mass index, and Helicobacter pylori

SUBMITTER: Kishikawa H 

PROVIDER: S-EPMC5249152 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature