Longitudinal Testing of Olfactory and Gustatory Function in Patients with Multiple Sclerosis.

ABSTRACT:

Background

The aim of the study was to investigate changes of the olfactory and gustatory capacity in patients with multiple sclerosis (MS).

Methodology

20 MS patients were tested longitudinally for 3 years after initial testing. The Threshold Discrimination Identification test (TDI) was used for subjective olfactometry. Objective olfactometry was performed by registering olfactory evoked potentials (OEP) by EEG. The Taste Strip Test (TST) was used for gustatory testing.

Results

45% of the patients showed olfactory dysfunction in the follow-up TDI test and 50% showed delayed OEP´s. 20% of the patients showed gustatory dysfunction on follow-up visit. The patients showed mild disease activity with 0,3 ± 0,5 relapses over the testing period and no significant change of t

SUBMITTER: Uecker FC 

PROVIDER: S-EPMC5249198 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature