Reduced nicotine content cigarettes and use of alternative nicotine products: exploratory trial.

ABSTRACT:

Aims

To compare the use of alternative nicotine products, smoking behavior and tobacco biomarker exposure in smokers unwilling to quit who were assigned randomly to normal nicotine content (NNC) cigarettes or very low nicotine content (VLNC) cigarettes.

Design

Randomized, parallel-arm 8-week study with assignment to VLNC (VLNC 1, n = 53) or NNC (NNC, n = 27) with access to non-cigarette combusted and non-combusted tobacco/nicotine products or to VLNC with access to only non-combusted products (VLNC2, n = 56).

Setting

Clinics in Minnesota, USA.

Participants

Smokers uninterested in quitting smoking with a mean [± standard deviation (SD)] age of 44 (± 14) years and smoking 16 (± seven) cigarettes/day; 51% female, 72% white.

Measurements

During the experimen

SUBMITTER: Hatsukami DK 

PROVIDER: S-EPMC5249662 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature