Distinct human immunodeficiency virus type 1 subtype A virus circulating in West Africa: sub-subtype A3.

ABSTRACT: Phylogenetic analyses demonstrate significant diversity in worldwide circulating strains of human immunodeficiency virus type 1 (HIV-1). Detailed studies have revealed a complex pattern of intersubtype recombinations, as well as evidence of sub-subtypes circulating in various populations. In this study, we characterized an HIV-1 strain that had previously been identified as a distinct subcluster within the subtype A radiation based on partial sequence data. These viruses were of particular interest given that we recently found that their prevalence was significantly higher in dually infected individuals compared to women who were singly infected with HIV-1. Five viruses isolated from commercial sex workers in Dakar, Senegal, were full-length PCR amplified and sequenced. Phylogenetic analys

SUBMITTER: Meloni ST 

PROVIDER: S-EPMC525043 | biostudies-literature | 2004 Nov

REPOSITORIES: biostudies-literature