Polymorphisms of the fimbria fim3 gene of Bordetella pertussis strains isolated in Canada.

ABSTRACT: The fim genes which code for the fimbria protective antigens present in both the inactivated whole-cell and acellular vaccines were analyzed in 86 Canadian Bordetella pertussis isolates. At least one of the novel mutations identified was found to involve a surface epitope that has been mapped by serum antibodies from infected or vaccinated subjects.

SUBMITTER: Tsang RS 

PROVIDER: S-EPMC525145 | biostudies-literature | 2004 Nov

REPOSITORIES: biostudies-literature