Retinal Microvascular Network and Microcirculation Assessments in High Myopia.

ABSTRACT:

Purpose

To investigate the changes of the retinal microvascular network and microcirculation in high myopia.

Design

A cross-sectional, matched, comparative clinical study.

Participants

Twenty eyes of 20 subjects with nonpathological high myopia (28 ± 5 years of age) with a refractive error of -6.31 ± 1.23 D (mean ± SD) and 20 eyes of 20 age- and sex-matched control subjects (30 ± 6 years of age) with a refractive error of -1.40 ± 1.00 D were recruited.

Methods

Optical coherence tomography angiography (OCTA) was used to image the retinal microvascular network, which was later quantified by fractal analysis (box counting [D_box], representing vessel density) in both superficial and deep vascular plexuses. The Retinal Function Imager was used to image th

SUBMITTER: Li M 

PROVIDER: S-EPMC5253241 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature