Aberrant neural networks for the recognition memory of socially relevant information in patients with schizophrenia.

ABSTRACT:

Introduction

Patients with schizophrenia exhibit several cognitive deficits, including memory impairment. Problems with recognition memory can hinder socially adaptive behavior. Previous investigations have suggested that altered activation of the frontotemporal area plays an important role in recognition memory impairment. However, the cerebral networks related to these deficits are not known. The aim of this study was to elucidate the brain networks required for recognizing socially relevant information in patients with schizophrenia performing an old-new recognition task.

Methods

Sixteen patients with schizophrenia and 16 controls participated in this study. First, the subjects performed the theme-identification task during functional magnetic resonance imaging. In this t

SUBMITTER: Oh J 

PROVIDER: S-EPMC5256185 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature