Key drivers of visual acuity gains in neovascular age-related macular degeneration in real life: findings from the AURA study.

ABSTRACT:

Background/aims

To identify predictive markers for the outcomes of anti-vascular endothelial growth factor therapy for neovascular age-related macular degeneration (nAMD).

Methods

AURA was a retrospective, observational, multicentre study that monitored the 2-year outcomes following intravitreal ranibizumab treatment in patients with nAMD. Using stepwise regression analysis, we evaluated the association between visual acuity outcomes, baseline characteristics and resource utilisation in order to determine which variables are significantly linked to outcomes in AURA. We also examined the relationship between visual acuity outcomes and number of injections received.

Results

Analyses were performed using data from year 1 (n=1695) and year 2 completers (n=1184). Logistic

SUBMITTER: Holz FG 

PROVIDER: S-EPMC5256408 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature