Kidney Function and Disability-Free Survival in Older Women.

ABSTRACT:

Objectives

To examine the prospective association between kidney function and three outcomes: survival to age 85 with functional independence, survival to age 85 with disability, and death before age 85.

Design

Prospective study.

Setting

Women's Health Initiative, conducted at 40 U.S. clinical centers.

Participants

Postmenopausal women enrolled between 1993 and 1998 with baseline biomarker assessments who had the potential to reach age 85 before September 2013 (N = 7,178).

Measurements

Kidney function was measured according to estimated glomerular filtration rate (eGFR) calculated from serum creatinine collected at baseline. Outcomes were survival to age 85 with functional independence, survival with disability, or death before age 85. Disability was def

SUBMITTER: Cavanaugh AM 

PROVIDER: S-EPMC5258685 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature