Clustering and evolutionary analysis of small RNAs identify regulatory siRNA clusters induced under drought stress in rice.

ABSTRACT:

Motivation

Drought tolerance is an important trait related to growth and yield in crop. Until now, drought related research has focused on coding genes. However, non-coding RNAs also respond significantly to environmental stimuli such as drought stress. Unfortunately, characterizing the role of siRNAs under drought stress is difficult since a large number of heterogenous siRNA species are expressed under drought stress and non-coding RNAs have very weak evolutionary conservation. Thus, to characterize the role of siRNAs, we need a well designed biological and bioinformatics strategy. In this paper, to characterize the function of siRNAs we developed and used a bioinformatics pipeline that includes a genomic-location based clustering technique and an evolutionary conservation tool.<

SUBMITTER: Jung I 

PROVIDER: S-EPMC5260113 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature