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Factors Associated with Medication Non-adherence in Patients with End-Stage Liver Disease.


ABSTRACT:

Background

Low medication adherence is known to contribute to worse health outcomes in the general population.

Aim

We aimed to evaluate the medication regimen and determine the adherence levels among patients with end-stage liver disease.

Methods

We measured adherence in patients awaiting liver transplantation at a single center using the 8-item Morisky Medication Adherence Scale (MMAS-8), with a score <8 classified as low adherence. Medication regimen complexity was assessed using the Medication Regimen Complexity Index (MRCI) tool. Factors associated with low adherence were identified by logistic regression.

Results

Of 181 patients, 33% were female, median age was 62, and model for end-stage liver disease (MELD) score was 13. The median (IQR) number of medica

SUBMITTER: Kuo SZ 

PROVIDER: S-EPMC5263169 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature