History of kidney stones and risk of chronic kidney disease: a meta-analysis.

ABSTRACT:

Background

Although the relationship between a history of kidney stones and chronic kidney disease (CKD) has been explored in many studies, it is still far from being well understood. Thus, we conducted a meta-analysis of studies comparing rates of CKD in patients with a history of kidney stones.

Methods

PubMed, EMBASE, and the reference lists of relevant articles were searched to identify observational studies related to the topic. A random-effects model was used to combine the study-specific risk estimates. We explored the potential heterogeneity by subgroup analyses and meta-regression analyses.

Results

Seven studies were included in this meta-analysis. Pooled results suggested that a history of kidney stones was associated with an increased adjusted risk estimate

SUBMITTER: Shang W 

PROVIDER: S-EPMC5267565 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature