Effects of Coenzyme Q10 on Markers of Inflammation: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background/objective

Chronic inflammation contributes to the onset and development of metabolic diseases. Clinical evidence has suggested that coenzyme Q10 (CoQ10) has some effects on inflammatory markers. However, these results are equivocal. The aim of this systematic review was to assess the effects of CoQ10 on serum levels of inflammatory markers in people with metabolic diseases.

Methods

Electronic databases were searched up to February 2016 for randomized controlled trials (RCTs). The outcome parameters were related to inflammatory factors, including interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α) and C reactive protein (CRP). RevMan software was used for meta-analysis. Meta-regression analysis, Egger line regression test and Begg rank correlation test were p

SUBMITTER: Zhai J 

PROVIDER: S-EPMC5268485 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature