Glucocorticoid-associated worsening in reversible cerebral vasoconstriction syndrome.

ABSTRACT:

Objective

Factors predicting poor outcome in patients with the reversible cerebral vasoconstriction syndrome (RCVS) have not been identified.

Methods

In this single-center retrospective study, we analyzed the clinical, brain imaging, and angiography data in 162 patients with RCVS. Univariable and multivariable regression analysis were performed to identify predictors of persistent (nontransient) clinical worsening, radiologic worsening, early angiographic progression, and poor discharge outcome (modified Rankin Scale score 4-6).

Results

The mean age was 44 ± 13 years; 78% of patients were women. Persistent clinical worsening occurred in 14% at 6.6 ± 4.1 days after symptom onset, radiologic worsening in 27% (mainly new infarcts), and angiographic progression in 15%. Cl

SUBMITTER: Singhal AB 

PROVIDER: S-EPMC5272793 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature