Cognitive and neural consequences of memory suppression in major depressive disorder.

ABSTRACT: Negative biases in cognition have been documented consistently in major depressive disorder (MDD), including difficulties in the ability to control the processing of negative material. Although negative information-processing biases have been studied using both behavioral and neuroimaging paradigms, relatively little research has been conducted examining the difficulties of depressed persons with inhibiting the retrieval of negative information from long-term memory. In this study, we used the think/no-think paradigm and functional magnetic resonance imaging to assess the cognitive and neural consequences of memory suppression in individuals diagnosed with depression and in healthy controls. The participants showed typical behavioral forgetting effects, but contrary to our hypotheses, ther

SUBMITTER: Sacchet MD 

PROVIDER: S-EPMC5272890 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature