Relationship between risk factor control and vascular events in the SAMMPRIS trial.

ABSTRACT:

Objective

The Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) study is the first stroke prevention trial to include protocol-driven intensive management of multiple risk factors. In this prespecified analysis, we aimed to investigate the relationship between risk factor control during follow-up and outcome of patients in the medical arm of SAMMPRIS.

Methods

Data from SAMMPRIS participants in the medical arm (n = 227) were analyzed. Risk factors were recorded at baseline, 30 days, 4 months, and then every 4 months for a mean follow-up of 32 months. For each patient, values for all risk factor measures were averaged and dichotomized as in or out of target.

Results

Participants who were out of target for syst

SUBMITTER: Turan TN 

PROVIDER: S-EPMC5272964 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature