Partial vs Radical Nephrectomy for T1-T2 Renal Masses in the Elderly: Comparison of Complications, Renal Function, and Oncologic Outcomes.

ABSTRACT:

Objective

To compare outcomes of partial nephrectomy (PN) and radical nephrectomy (RN) in patients 65 years and older.

Materials and methods

Our institutional renal mass registry was queried for patients 65 and older with solitary cT1-T2 renal mass resected by PN or RN. Clinicopathologic features and perioperative outcomes were compared between groups. Renal function outcomes measured by change in estimated glomerular filtration rate (eGFR) and freedom from eGFR< 45 mL/min/1.73 m² were analyzed. Multivariate Cox proportional hazard models for overall survival and cancer-specific survival were analyzed.

Results

Overall, 787 patients met inclusion criteria. Of these, 437 (55.5%) underwent PN and 350 (44.5%) underwent RN. Median follow-up was 36 months. Patien

SUBMITTER: An JY 

PROVIDER: S-EPMC5274548 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature