Heterogeneous impact of alcohol consumption according to treatment method on survival in head and neck cancer: A prospective study.

ABSTRACT: Alcohol consumption is an established risk factor, and also a potential prognostic factor, for squamous cell carcinoma of the head and neck (HNSCC). However, little is known about whether the prognostic impact of alcohol consumption differs by treatment method. We evaluated the association between alcohol drinking and survival by treatment method to the primary site in 427 patients with HNSCC treated between 2005 and 2013 at Aichi Cancer Center Central Hospital (Nagoya, Japan). The impact of alcohol on prognosis was measured by multivariable Cox regression analysis adjusted for established prognostic factors. Among all HNSCC patients, the overall survival rate was significantly poorer with increased levels of alcohol consumption in multivariable analysis (trend P = 0.038). Stratification b

SUBMITTER: Sawabe M 

PROVIDER: S-EPMC5276823 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature