Patterns and characterization of COPD exacerbations using real-time data collection.

ABSTRACT:

Introduction

Patients with chronic obstructive pulmonary disease often experience exacerbations. These events are important as they are a major cause of morbidity and mortality. Recently, it has been increasingly recognized that patients may experience symptoms suggestive of an exacerbation but do not seek treatment, which are referred to as unreported or untreated exacerbations. Symptom diaries used in clinical trials have the benefit of identifying both treated and untreated exacerbation events.

Methods

The Kamada study was a multicenter, double-blind randomized controlled trial of inhaled augmentation therapy in alpha-1 antitrypsin deficiency (AATD). A retrospective review of daily electronic symptom diary cards was undertaken from the two leading centers to identify symp

SUBMITTER: Ejiofor SI 

PROVIDER: S-EPMC5279955 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature