Identifying the Metabolic Differences of a Fast-Growth Phenotype in Synechococcus UTEX 2973.

ABSTRACT: The photosynthetic capabilities of cyanobacteria make them interesting candidates for industrial bioproduction. One obstacle to large-scale implementation of cyanobacteria is their limited growth rates as compared to industrial mainstays. Synechococcus UTEX 2973, a strain closely related to Synechococcus PCC 7942, was recently identified as having the fastest measured growth rate among cyanobacteria. To facilitate the development of 2973 as a model organism we developed in this study the genome-scale metabolic model iSyu683. Experimental data were used to define CO₂ uptake rates as well as the biomass compositions for each strain. The inclusion of constraints based on experimental measurements of CO₂ uptake resulted in a ratio of the growth rates of Synechococcus 2973

SUBMITTER: Mueller TJ 

PROVIDER: S-EPMC5282492 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature