Ontology highlight
ABSTRACT:
SUBMITTER: Uher T
PROVIDER: S-EPMC5282956 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Uher Tomas T Uher Tomas T Fellows Kelly K Horakova Dana D Zivadinov Robert R Vaneckova Manuela M Sobisek Lukas L Tyblova Michaela M Seidl Zdenek Z Krasensky Jan J Bergsland Niels N Weinstock-Guttman Bianca B Havrdova Eva E Ramanathan Murali M
Journal of lipid research 20161206 2
The purpose of this work was to determine whether changes in cholesterol profiles after interferon-β (IFN-β)1a treatment initiation following the first demyelinating event suggestive of multiple sclerosis are associated with clinical and MRI outcomes over 4 years. A group of 131 patients (age: 27.9 ± 7.8 years, 63% female) with serial 3-monthly clinical and 12-monthly MRI follow-ups over 4 years were investigated. Serum cholesterol profiles, including total cholesterol (TC), HDL cholesterol (HDL ...[more]