Nasal high flow reduces dead space.

ABSTRACT: Recent studies show that nasal high flow (NHF) therapy can support ventilation in patients with acute or chronic respiratory disorders. Clearance of dead space has been suggested as being the key mechanism of respiratory support with NHF therapy. The hypothesis of this study was that NHF in a dose-dependent manner can clear dead space of the upper airways from expired air and decrease rebreathing. The randomized crossover study involved 10 volunteers using scintigraphy with ^81mKrypton (^81mKr) gas during a breath-holding maneuver with closed mouth and in 3 nasally breathing tracheotomized patients by volumetric capnography and oximetry through sampling CO₂ and O₂ in the trachea and measuring the inspired volume with inductance plethysmography foll

SUBMITTER: Moller W 

PROVIDER: S-EPMC5283847 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature