Predictive Validity of the Beers and Screening Tool of Older Persons' Potentially Inappropriate Prescriptions (STOPP) Criteria to Detect Adverse Drug Events, Hospitalizations, and Emergency Department Visits in the United States.

ABSTRACT:

Objectives

To compare the predictive validity of the 2003 Beers, 2012 American Geriatrics Society (AGS) Beers, and Screening Tool of Older Persons' potentially inappropriate Prescriptions (STOPP) criteria.

Design

Retrospective cohort.

Setting

Managed care administrative claims data from 2006 to 2009.

Participants

Commercially insured persons aged 65 and older in the United States (N=174,275).

Measurements

Association between adverse drug events (ADEs), emergency department (ED) visits, and hospitalization outcomes and inappropriate medication use using time-varying Cox proportional hazard models. Measures of model discrimination (c-index) and hazard ratios (HRs) were calculated to compare unadjusted and adjusted models for associations.

Results

Th

SUBMITTER: Brown JD 

PROVIDER: S-EPMC5287350 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature