Association Between Serum Calcium Level and Extent of Bleeding in Patients With Intracerebral Hemorrhage.

ABSTRACT:

Importance

Calcium is a key cofactor of the coagulation cascade and may play a role in the pathophysiology of intracerebral hemorrhage (ICH).

Objective

To investigate whether a low serum calcium level is associated with an increase in the extent of bleeding in patients with ICH as measured by baseline hematoma volume and risk of hematoma expansion.

Design, setting, and participants

Prospective cohort study of 2103 consecutive patients with primary ICH ascertained during the period between 1994 and 2015 at an academic medical center. The statistical analysis was performed in January 2016.

Main outcomes and measures

Total calcium level was measured on admission, and hypocalcemia was defined as a serum calcium level of less than 8.4 mg/dL. Baseline and follow-up h

SUBMITTER: Morotti A 

PROVIDER: S-EPMC5287716 | biostudies-literature | 2016 Nov

REPOSITORIES: biostudies-literature