Outer Membrane Proteins form Specific Patterns in Antibiotic-Resistant Edwardsiella tarda.

ABSTRACT: Outer membrane proteins of Gram-negative bacteria play key roles in antibiotic resistance. However, it is unknown whether outer membrane proteins that respond to antibiotics behave in a specific manner. The present study specifically investigated the differentially expressed outer membrane proteins of an antibiotic-resistant bacterium, Edwardsiella tarda, a Gram-negative pathogen that can lead to unnecessary mass medication of antimicrobials and consequently resistance development in aquaculture and a spectrum of intestinal and extraintestinal diseases in humans. The comparison of a clinically isolated strain to the laboratory derived kanamycin-, tetracycline-, or chloramphenicol-resistant strains identified their respective outer membrane proteins expression patterns, which are dis

SUBMITTER: Peng B 

PROVIDER: S-EPMC5288343 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature