Influences of pH and Iron Concentration on the Salivary Microbiome in Individual Humans with and without Caries.

ABSTRACT: This study aimed to identify the differences in the oral microbial communities in saliva from patients with and without caries by performing sequencing with the Illumina MiSeq platform, as well as to further assess their relationships with environmental factors (salivary pH and iron concentration). Forty-three volunteers were selected, including 21 subjects with and 22 without caries, from one village in Gansu, China. Based on 966,255 trimmed sequences and clustering at the 97% similarity level, 1,303 species-level operational taxonomic units were generated. The sequencing data for the two groups revealed that (i) particular distribution patterns (synergistic effects or competition) existed in the subjects with and without caries at both the genus and species levels and (ii) both the saliv

SUBMITTER: Zhou J 

PROVIDER: S-EPMC5288818 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature