Interfacial Ca²⁺ environments in nanocrystalline apatites revealed by dynamic nuclear polarization enhanced ⁴³Ca NMR spectroscopy.

ABSTRACT: The interfaces within bones, teeth and other hybrid biomaterials are of paramount importance but remain particularly difficult to characterize at the molecular level because both sensitive and selective techniques are mandatory. Here, it is demonstrated that unprecedented insights into calcium environments, for example the differentiation of surface and core species of hydroxyapatite nanoparticles, can be obtained using solid-state NMR, when combined with dynamic nuclear polarization. Although calcium represents an ideal NMR target here (and de facto for a large variety of calcium-derived materials), its stable NMR-active isotope, calcium-43, is a highly unreceptive probe. Using the sensitivity gains from dynamic nuclear polarization, not only could calcium-43 NMR spectra be obtained easil

SUBMITTER: Lee D 

PROVIDER: S-EPMC5290151 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature