Trends in assisted ventilation and outcome for obstructive pulmonary disease exacerbations. A nationwide study.

ABSTRACT:

Background

Non-invasive ventilation (NIV) has been used for decades in treatment of exacerbations of chronic obstructive pulmonary disease (COPD). The impact of the changing use of assisted ventilation in acute exacerbations on outcomes has not been fully elucidated and we aimed to describe these changes in the Danish population and describe their consequences for mortality.

Methods

A register-based study was conducted of a cohort of 12,847 patients admitted for acute exacerbation of COPD (AECOPD) from 2004 through 2011, treated with invasive mechanical ventilation (IMV) or NIV for the first time. Age, sex, in-hospital mortality rates, time to death or readmission for AECOPD were established and changes over time tracked.

Results

The number of admissions for AECOPD wh

SUBMITTER: Toft-Petersen AP 

PROVIDER: S-EPMC5291443 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature