Identifying radiation-induced survivorship syndromes affecting bowel health in a cohort of gynecological cancer survivors.

ABSTRACT:

Background

During radiotherapy unwanted radiation to normal tissue surrounding the tumor triggers survivorship diseases; we lack a nosology for radiation-induced survivorship diseases that decrease bowel health and we do not know which symptoms are related to which diseases.

Methods

Gynecological-cancer survivors were followed-up two to 15 years after having undergone radiotherapy; they reported in a postal questionnaire the frequency of 28 different symptoms related to bowel health. Population-based controls gave the same information. With a modified factor analysis, we determined the optimal number of factors, factor loadings for each symptom, factor-specific factor-loading cutoffs and factor scores.

Results

Altogether data from 623 survivors and 344 population-base

SUBMITTER: Steineck G 

PROVIDER: S-EPMC5291512 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature