Neurodevelopment in Early Childhood Affected by Prenatal Lead Exposure and Iron Intake.

ABSTRACT: No safe threshold level of lead exposure in children has been recognized. Also, the information on shielding effect of maternal dietary iron intake during pregnancy on the adverse effects of prenatal lead exposure on children's postnatal neurocognitive development is very limited. We examined the association of prenatal lead exposure and neurodevelopment in children at 6, 12, 24, and 36 months and the protective action of maternal dietary iron intake against the impact of lead exposure. The study participants comprise 965 pregnant women and their subsequent offspring of the total participants enrolled in the Mothers and Children's environmental health study: a prospective birth cohort study. Generalized linear model and linear mixed model analysis were performed to analyze the effect of pr

SUBMITTER: Shah-Kulkarni S 

PROVIDER: S-EPMC5291557 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature