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Two tonB systems function in iron transport in Vibrio anguillarum, but only one is essential for virulence.


ABSTRACT: We have identified two functional tonB systems in the marine fish pathogen Vibrio anguillarum, tonB1 and tonB2. Each of the tonB genes is transcribed in an operon with the cognate exbB and exbD genes in response to iron limitation. Only tonB2 is essential for transport of ferric anguibactin and virulence.

SUBMITTER: Stork M 

PROVIDER: S-EPMC529167 | biostudies-literature | 2004 Dec

REPOSITORIES: biostudies-literature

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Two tonB systems function in iron transport in Vibrio anguillarum, but only one is essential for virulence.

Stork Michiel M   Di Lorenzo Manuela M   Mouriño Susana S   Osorio Carlos R CR   Lemos Manuel L ML   Crosa Jorge H JH  

Infection and immunity 20041201 12


We have identified two functional tonB systems in the marine fish pathogen Vibrio anguillarum, tonB1 and tonB2. Each of the tonB genes is transcribed in an operon with the cognate exbB and exbD genes in response to iron limitation. Only tonB2 is essential for transport of ferric anguibactin and virulence. ...[more]

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