A compendium of developmental gene expression in Lake Malawi cichlid fishes.

ABSTRACT:

Background

Lake Malawi cichlids represent one of a growing number of vertebrate models used to uncover the genetic and developmental basis of trait diversity. Rapid evolutionary radiation has resulted in species that share similar genomes but differ markedly in phenotypes including brains and behavior, nuptial coloration and the craniofacial skeleton. Research has begun to identify the genes, as well as the molecular and developmental pathways that underlie trait divergence.

Results

We assemble a compendium of gene expression for Lake Malawi cichlids, across pharyngula (the phylotypic stage) and larval stages of development, encompassing hundreds of gene transcripts. We chart patterns of expression in Bone morphogenetic protein (BMP), Fibroblast growth factor (FGF), Hedgehog

SUBMITTER: Bloomquist RF 

PROVIDER: S-EPMC5291978 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature