Attention bias in older women with remitted depression is associated with enhanced amygdala activity and functional connectivity.

ABSTRACT:

Background

Cognitive bias is a common characteristic of major depressive disorder (MDD) and is posited to remain during remission and contribute to recurrence risk. Attention bias may be related to enhanced amygdala activity or altered amygdala functional connectivity in depression. The current study examined attention bias, brain activity for emotional images, and functional connectivity in post-menopausal women with and without a history of major depression.

Methods

Attention bias for emotionally valenced images was examined in 33 postmenopausal women with (n=12) and without (n=21) a history of major depression using an emotion dot probe task during fMRI. Group differences in amygdala activity and functional connectivity were assessed using fMRI and examined for correlatio

SUBMITTER: Albert K 

PROVIDER: S-EPMC5292067 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature