NFAT5 genes are part of the osmotic regulatory system in Atlantic salmon (Salmo salar).
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ABSTRACT: The anadromous Atlantic salmon utilizes both fresh and salt water (FW and SW) habitats during its life cycle. The parr-smolt transformation (PST) is an important developmental transition from a FW adapted juvenile parr to a SW adapted smolt. Physiological changes in osmoregulatory tissues, particularly the gill, are key in maintaining effective ion regulation during PST. Changes are initiated prior to SW exposure (preparative phase), and are completed when smolts enter the sea (activational phase) where osmotic stress may directly stimulate changes in gene expression. In this paper we identify 4 nuclear factor of activated T cells (NFAT5, an osmotic stress transcription factor) paralogues in Atlantic salmon, which showed strong homology in characterized functional domains with those identi
SUBMITTER: Lorgen M
PROVIDER: S-EPMC5292104 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
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