Association of Fitness in Young Adulthood With Survival and Cardiovascular Risk: The Coronary Artery Risk Development in Young Adults (CARDIA) Study.

ABSTRACT:

Importance

Although cardiorespiratory fitness (CRF) is prognostic in older adults, the effect of CRF during early adulthood on long-term cardiovascular structure, function, and prognosis is less clear.

Objective

To examine whether CRF in young adults is associated with long-term clinical outcome and subclinical cardiovascular disease (CVD).

Design, setting, and participants

Prospective study of 4872 US adults aged 18 to 30 years who underwent treadmill exercise testing at a baseline study visit from March 25, 1985, to June 7, 1986, and 2472 individuals who underwent a second treadmill test 7 years later. Median follow-up was 26.9 years, with assessment of obesity, left ventricular mass and strain, coronary artery calcification (CAC), and vital status and incident CVD.

SUBMITTER: Shah RV 

PROVIDER: S-EPMC5292201 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature