Age and duration of testosterone therapy predict time to return of sperm count after human chorionic gonadotropin therapy.

ABSTRACT:

Objective

To determine factors that influence sperm recovery after T-associated infertility.

Design

Clinical retrospective study.

Setting

Academic male-infertility urology clinic.

Patient(s)

Sixty-six men who presented with infertility after T use.

Intervention(s)

T cessation and combination high-dose hCG and selective estrogen modulator (SERM) therapy.

Main outcome measure(s)

Whether patients successfully achieved or failed to achieve a total motile count (TMC) of greater than 5 million sperm within 12 months of T cessation and initiation of therapy.

Result(s)

A TMC of greater than 5 million sperm was achieved by 46 men (70%). Both increased age and duration of T use directly correlated with time to sperm recovery at both 6 and 12 months o

SUBMITTER: Kohn TP 

PROVIDER: S-EPMC5292276 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature