Neoadjuvant or adjuvant therapy for resectable esophageal cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

Carcinoma of the esophagus is an aggressive malignancy with an increasing incidence. Its virulence, in terms of symptoms and mortality, justifies a continued search for optimal therapy. The large and growing number of patients affected, the high mortality rates, the worldwide geographic variation in practice, and the large body of good quality research warrants a systematic review with meta-analysis.

Methods

A systematic review and meta-analysis investigating the impact of neoadjuvant or adjuvant therapy on resectable thoracic esophageal cancer to inform evidence-based practice was produced.MEDLINE, CANCERLIT, Cochrane Library, EMBASE, and abstracts from the American Society of Clinical Oncology and the American Society for Therapeutic Radiology and Oncology were

SUBMITTER: Malthaner RA 

PROVIDER: S-EPMC529457 | biostudies-literature | 2004 Sep

REPOSITORIES: biostudies-literature