Exon-Enriched Libraries Reveal Large Genic Differences Between <i>Aedes aegypti</i> from Senegal, West Africa, and Populations Outside Africa.

ABSTRACT: Aedes aegypti is one of the most studied mosquito species, and the principal vector of several arboviruses pathogenic to humans. Recently failure to oviposit, low fecundity, and poor egg-to-adult survival were observed when Ae. aegypti from Senegal (SenAae) West Africa were crossed with Ae. aegypti (Aaa) from outside of Africa, and in SenAae intercrosses. Fluorescent in situ hybridization analyses indicated rearrangements on chromosome 1, and pericentric inversions on chromosomes 2 and 3. Herein, high throughput sequencing (HTS) of exon-enriched libraries was used to compare chromosome-wide genetic diversity among Aaa collections from rural Thailand and Mexico, a sylvatic collection from southeastern Senegal (PK10), and an urban colle

SUBMITTER: Dickson LB 

PROVIDER: S-EPMC5295602 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature