Cost-effectiveness of maternal influenza immunization in Bamako, Mali: A decision analysis.

ABSTRACT:

Background

Maternal influenza immunization has gained traction as a strategy to diminish maternal and neonatal mortality. However, efforts to vaccinate pregnant women against influenza in developing countries will require substantial investment. We present cost-effectiveness estimates of maternal influenza immunization based on clinical trial data from Bamako, Mali.

Methods

We parameterized a decision-tree model using prospectively collected trial data on influenza incidence, vaccine efficacy, and direct and indirect influenza-related healthcare expenditures. Since clinical trial participants likely had better access to care than the general Malian population, we also simulated scenarios with poor access to care, including decreased healthcare resource utilization and worse

SUBMITTER: Orenstein EW 

PROVIDER: S-EPMC5295679 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature