The association between environmental exposures during childhood and the subsequent development of Crohn's disease: A score analysis approach.

ABSTRACT:

Background

Environmental factors during childhood are thought to play a role in the aetiology of Crohn's Disease (CD). In South Africa, recently published work based on an investigation of 14 childhood environmental exposures during 3 age intervals (0-5, 6-10 and 11-18 years) has provided insight into the role of timing of exposure in the future development of CD. The 'overlapping' contribution of the investigated variables however, remains unclear. The aim of this study was to perform a post hoc analysis using this data and investigate the extent to which each variable contributes to the subsequent development of CD relative to each aforementioned age interval, based on a score analysis approach.

Methods

Three methods were used for the score analysis. Two methods employed t

SUBMITTER: Sabe VT 

PROVIDER: S-EPMC5295693 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature