Phenotype and multipotency of rabbit (Oryctolagus cuniculus) amniotic stem cells.

ABSTRACT:

Background

Stem cells are capable of unlimited self-renewal and are able to remain undifferentiated for extended periods of time prior to their differentiation into specific cell lineages. Because of the issues (ethical and religious) involved in the use of embryonic stem cells and the limited plasticity of adult stem cells, an alternative cell source could be foetal stem cells derived from extra-embryonic tissue, which are highly proliferative, grow in vitro and possess interesting immunogenic characteristics. As a result, the amniotic membrane of several species has been studied as an important new source of stem cells.

Methods

Here, we cultured and characterized mesenchymal progenitor cells derived from the rabbit amniotic membrane, and investigated their differentiation

SUBMITTER: Borghesi J 

PROVIDER: S-EPMC5297200 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature