Premenopausal abnormal uterine bleeding and risk of endometrial cancer.

ABSTRACT:

Background

Endometrial biopsies are undertaken in premenopausal women with abnormal uterine bleeding but the risk of endometrial cancer or atypical hyperplasia is unclear.

Objectives

To conduct a systematic literature review to establish the risk of endometrial cancer and atypical hyperplasia in premenopausal women with abnormal uterine bleeding.

Search strategy

Search of PubMed, Embase and the Cochrane Library from database inception to August 2015.

Selection criteria

Studies reporting rates of endometrial cancer and/or atypical hyperplasia in women with premenopausal abnormal uterine bleeding.

Data collection and analysis

Data were independently extracted by two reviewers and cross-checked. For each outcome, the risk and a 95% CI were estimated using l

SUBMITTER: Pennant ME 

PROVIDER: S-EPMC5297977 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature